* For illustration purpose only
Periactin medication is a tableted drug, an antagonist of histamine and serotonin. It is prescribed in the treatment of anorexic conditions, with exhaustion caused by a lack of appetite.
Periactin is an antagonist of serotonin and histamine and has the ability to stimulate the appetite. This feature provokes the mass use of the drug, not for its intended purpose, but as a means to increase weight, especially in patients suffering from muscle loss associated with AIDS, cancer or other debilitating diseases.
Thus, the drug is used to treat allergic diseases (acute and chronic urticaria, serum sickness, pollinosis, vasomotor rhinitis, contact dermatitis, neurodermatitis, angioedema, allergic reactions to medication, etc.), as well as with migraine (mainly due to the anti serotonin effect), loss of appetite of various etiologies (neurogenic anorexia, chronic diseases, etc.). Due to the fact that histamine and serotonin increase the secretion of pancreatic juice, it has also been proposed to use Periactin in the complex therapy of chronic pancreatitis.
Dosage and direction
Periactin dosage and intake. To increase the appetite, adults are prescribed 1 / 2-1 tablet 3-4 times a day or 1-2 teaspoons of syrup 3-4 times a day; children from 2 to 6 years old - no more than 2 tablets or 4 teaspoons of syrup per day; children from 6 to 14 years old - no more than 3 tablets or 6 teaspoons of syrup per day.
As for Periactin side effects, it should be mentioned that drowsiness, dry mouth, in rare cases - anxiety, ataxia, dizziness, nausea, skin rash may occur.
Possible side effect
They may include an allergic reaction:
• difficulty breathing;
• swelling of your face, lips, tongue, or throat.
Also, the most possible side effects include:
• confusion, hallucinations, unusual thoughts or behaviour;
• seizure (convulsions);
• ringing in your ears;
• feeling like you might pass out;
• fast or pounding heartbeats;
• easy bruising or bleeding; urinating less than usual or not at all;
• or pale or yellowed skin, dark coloured urine, fever, or unusual weakness.
Less serious include:
• mild drowsiness, dizziness, or spinning sensation;
• restlessness or excitability (especially in children);
• sleep problems (insomnia), tired feeling; numbness or tingly feeling;
• increased sweating or urination;
• blurred vision;
• appetite changes;
• dry mouth or nose, upset stomach;
• or nausea, diarrhoea, constipation.
If you experience one of them stop using Periactin and tell your doctor as soon as possible. Also, consult with your doctor about any side effect that seems unusual.
Periactin interacts with such medication as isocarboxazid (Marplan); phenelzine (Nardil); rasagiline (Azilect); selegiline (Eldepryl, Emsam); or tranylcypromine (Parnate). Also, note that the interaction between two medications does not always mean that you must stop taking one of them. As usual, it affects the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.
Medically reviewed by Dr. Josette Davignon
Last updated: 28.05.2021
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