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Pariet (Rabeprazole)
Pariet (Rabeprazole)

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Pariet (Rabeprazole)

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Commercial name: Pariet
Active Ingredient: Rabeprazole
Production form: Pills 
Utilization: Reduces the amount of acid in the stomach and relieves symptoms of gastroesophageal reflux disease
Available Dosages: 10mg and 20mg
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Description
Common use
        Parietis an antiulcer medication which inhibits a proton pump (PPIs) and blocks the production of acid by the stomach. Biochemically it blocks the (H+,K+)-ATPase enzyme system hereby inhibiting the final stage of hydrochloric acid production. After peroral intake of Parietantisecretorial effect is reached during one hour and is maximal in 2-4 hours. This medication is used to treat ulcers in stomach, Zollinger-Ellison syndrome, gastroesophageal reflux disease, to eradicate Helicobacter pylori in patients with ulcers in stomach or chronic gastritis.

Dosage and directions
        Dosage should be administered by your doctor depending on your condition. Usually in patients with an acute duodenal ulcer and c it is recommended to take 1 tab (20 mg) in morning one time a day during 4-6 weeks. When treating H. pylori infection, Pariet may be needed for only a week. Follow all recommendations of your doctor and do not take this drug in larger amounts than it was prescribed to you. Tablets should be swallowed whole. Do not crush, split or chew them. Take Pariet with or without meals with a big glass of water since food has little effect on its absorption.

Precautions
        Notify your doctor if you have severe liver disease, cancer of stomach before to take this drug. Use of  Pariet in children is not recommended. It is not expected to be harmful to an unborn baby, though inform your doctor if you are pregnant or breastfeeding. Some conditions are treated with a combination of Pariet and antibiotics, so to achieve maximal effect from treatment, use all of your medications as directed by your doctor.

Contraindications
        Pregnancy, breastfeeding, hypersensitivity to Pariet or a substituted benzimidazoles: omeprazole (Prilosec, Zegerid), lansoprazole (Prevacid), pantoprazole (Protonix), rabeprazole (Pariet ), and esomeprazole (Nexium).

Possible side effect
        Together with symptoms of allergy (hives, rash, swelling of tongue and face) such side effects may occur: headache, dizziness, dry mouth, upset stomach or diarrhea, constipation, insomnia, nervousness, rash, or itching. Contact your doctor for help if any of the listed side effects is severe or persistent.

Drug interaction
        Co-administration with the medications which absorption depends on acidity of the stomach causes interaction of medications. Pariet and other PPIs reduce the absorption and concentration in blood of ketoconazole (Nizoral) and increase the absorption and concentration in blood of digoxin (Lanoxin) causing reduction of effectiveness of the former and increase of toxicity of the latter.

Missed dose
        If you missed a dose take the medication as soon as you remember. If it is almost time of your next dose just skip its intake and return to your regular schedule.

Overdose
        Symptoms of Pariet overdose are unknown. If you consider that you took too much of the drug to seek emergency medical attention.

Storage
        Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets.

Josette-Davignon

Medically reviewed by Dr. Josette Davignon

Last updated: 28.05.2021

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