This medication belongs to the group of calcium channel blockers. Norvasc selectively blocks channels of L-type (one of six types of channels in tissues) located in a vascular wall, myocardial and in particular in cells of conducting and contractile systems of myocardium. By blocking Ca+ ions transfer through membrane Norvasc decreases tone of vessels, arterial pressure. The medication is used to treat hypertension, ischemic heart disease, angina.
Dosage and direction
Do not take this drug if it was not administered to you. Follow all directions of your doctor. It is possible to take Norvasc with or without food. As it is metabolized in the liver it should be administered cautiously in patients with liver failure.
Avoid drinking alcohol. Before taking Norvasc, inform your doctor if you have congestive heart failure or liver disease.
Individual hypersensitivity, arterial hypotension, cardiogenic shock, pregnancy, breastfeeding. Cautiousness is important when Norvasc is administered in patients with chronic heart failure diabetes, lipid metabolism disorders, liver failure and to persons younger 18 y.o.
Possible side effect
The most common side effects are oedema of lower extremities and headache. Contact your doctor for medical attention if you feel them and also swelling in your hands, ankles, or feet, chest pain, slow, fast, or pounding heartbeats, easy bruising or bleeding, unusual weakness, numbness, burning, pain, or tingly feeling, jaundice.
Medications which contain Á2+ may decrease Norvasc effect. Non-steroid anti-inflammatory medications and estrogens may decrease the effectiveness of Norvasc. Diuretics may increase Norvasc activity. Concomitant taking with medications containing lithium might aggravate their toxicity.
If you forgot to take a dose take it as soon as you remember unless it is almost time for the next intake. If so do not take the missed dose and resume your regular schedule. Do not compensate for the missed dose by taking an extra one.
If you experience tingly feeling, severe dizziness, and fainting seek for immediate medical help.
Keep at room temperature, 15-30 C (59-86 F), in a light-resistant container away from moisture.