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Eldepryl (Selegiline)
Eldepryl (Selegiline)

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Eldepryl (Selegiline)

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Category: Mental Health
Commercial Name: Eldepryl
Principal Ingredient: Selegiline
Utilization: Treats Parkinson Syndrome
Production form: Pills 
Available Dosage: 5mg
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Description
Common use
        Eldepryl is a monoamine oxidase inhibitor, which used to treat the symptoms of Parkinson's disease. This is a case of the brain that affects motion. People with Parkinson's disease do not have enough nerve cells in the part of the brain that controls movement. These nerve cells produce a substance called dopamine. It is a lack of dopamine which causes problems with movement. Eldepryl Tablets keep dopamine around longer, helping with difficulties in movement. Eldepryl has no anti-Parkinson effects of its own and must always be given in combination with levodopa/carbidopa.

Dosage and direction
        Take it orally every day after breakfast and lunch. Do not drink or eat anything for at least 5 minutes after taking an Eldepryl orally disintegrating tablet. The recommended dose for adults is 10 mg per day divided into 2 smaller doses of 5 mg. Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It helps you to get the best results.

Precautions
    You must not eat foods that are high in tyramine, including pickled herring, air-dried meats, aged or fermented meats, poultry, sausage or salami, and any spoiled or improperly stored beef, fish, or liver; aged cheeses, including blue, brick, Bourgault, brie, cheddar, camembert, Emmenthaler, parmesan, romano, gruyere, Roquefort, stilton and swiss; beer from a tap, a beer that has not been pasteurized; over-the-counter supplements or cough and cold medicines that contain tyramine; sauerkraut, soybeans, soy sauce, tofu, miso soup, bean curd, fava beans; or yeast extracts. Eating tyramine while you are taking this drug can increase your blood pressure to dangerous levels which could cause life-threatening side effects. Eldepryl should be administered cautiously to patients with peptic or duodenal ulcer, labile hypertension, cardiac arrhythmias, severe angina pectoris, severe liver or kidney dysfunction or psychosis. In higher doses (>30 mg daily) the attenuation of selegiline begins to decrease resulting in increased inhibition of MAO-A. Lightheadedness, dizziness, or fainting may intervene, especially when you get up from a lying or sitting position. So you may get up slowly, but if the problem continues or gets worse, consult to your doctor. Eldepryl should not be used during pregnancy, becoming pregnant or lactating without doctor's advice. Do not use Eldepryl before breast-feeding without doctor's permission.

Contraindications
        Eldepryl is not allowed to people who are hypersensitive to selegiline or other components of the formulation. Do not take Demerol or such types of narcotic while you are taking Eldepryl. Also do not use Eldepryl if you have used any of the following drugs within the past 14 days: meperidine, propoxyphene, or tramadol; methadone; cough or cold medicine that contains dextromethorphan; or other MAO inhibitors such as isocarboxazid, tranylcypromine, phenelzine, rasagiline, or transdermal selegiline.

Possible side effect
        They may include all types of an allergic reaction. Also, the most possible side effects include confusion, sudden and severe headache, blurred vision, nausea, problems with speech or balance, vomiting, seizure, chest pain and sudden numbness or weakness; feeling light-headed, fainting; hallucinations; feeling restless, agitated, or irritable; twitching muscle movements; painful or difficult urination. Less serious include dizziness, weakness; sleep problems (insomnia); runny or stuffy nose; back pain; constipation; If you experience one of them stop using Eldepryl and tell your doctor as soon as possible. Also, consult with your doctor about any side effect that seems unusual.

Drug interaction
        Eldepryl interact with the following list of drugs: diet pills or cold medicines that contain ephedrine, pseudoephedrine, or phenylephrine; carbamazepine; nafcillin; rifampin; an antidepressant such as amitriptyline, amoxapine, bupropion, citalopram, clomipramine, desipramine, doxepin, duloxetine, escitalopram, fluoxetine, fluvoxamine, imipramine, nortriptyline, paroxetine, protriptyline, sertraline, venlafaxine, or trimipramine; phenobarbital. Also, note that the interaction between two medications does not always mean that you must stop taking one of them. As usual, it affects the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

Missed dose
        If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usual dose next day in the same regularly time.

Overdose
        Symptoms of Eldepryl overdose may include severe headache, vision problems, sweating, hallucinations, feeling light-headed, cool or clammy skin, fast or uneven heart rate, fainting, or seizure. If you experience one of them or any unusual symptoms call your doctor immediately.

Storage
        Store at room temperature between 20-25 C (68-77 F).

Josette-Davignon

Medically reviewed by Dr. Josette Davignon

Last updated: 27.10.2021

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